Disappointment has once again been deal between medick and scientists as , for the second fourth dimension , the hopes of a remedy for HIV have been dashed by the return of the virus in a tiddler that was consider to be cleared of contagion . Just like the famous “ Mississippi infant ” that made headlines last fall , the child was give strong-growing therapy before long after being bear to an HIV - positive mother . encourage by the former vitrine , therapy was finally stopped in the toddler and he was monitored nearly . But the virus soon come restrain back in both children , demonstrating that early handling is insufficient to altogether free the consistence of transmission .
As report in theLancet , the baby was born back in 2009 in Milan to a woman with a chronicle of intravenous drug use . She was unaware of her position at the time of labor , but rapid examination revealed that she was HIV - irrefutable and had mellow levels of the computer virus in her body . Twelve hours after he was stomach , numerous different trial were perform to make certain that any signs of the virus were not missed , and unfortunately they incur that he too was infected and also had a very mellow viral load ( over 150,000 copy of the computer virus per cubic centimeter of line ) .
Doctors then immediately begin aggressive therapy , starting off with two different drug and then add a third on twenty-four hour period four . The baby answer well to the drug and his viral load dropped to indiscernible grade within just six month . For the next two and a half years , all tests for the virus persist electronegative . Because of the reported success of the Mississippi sister , the nestling ’s Doctor and mother agreed to stop the treatment .
Although the doctors could n’t detect any sign of rebound within the first hebdomad , his resistant system of rules was showingtelltale signsof transmission , such as an growth in trigger off white blood cells . Just one hebdomad later , further tests expose that his viral lode had shoot up to almost 37,000 copies per milliliter of descent . This mean that although the drugs were effectively insure his infection , they had once again failed to straighten out the so - address viral reservoirs where the virus hides in sure population of prison cell . This remains a major hurdle in HIV treatment and until this can be achieved , antiretroviral drug can not be curative .
While this event is disappointing , most doctors are in understanding that this aggressive early approaching in babe conduct with HIV has merit . “ I think we will find a functional therapeutic . We just have n’t detect it yet,”said Dr. Michael Horberg , director of HIV / AIDS for Kaiser Permanente . “ That does n’t mean the principles of a scheme of reach hard for an extended time period should not make . ”
[ ViaThe Lancet , The LancetandWebMD ]
